Journal of Laboratory Physicians
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ORIGINAL ARTICLE
Year : 2009  |  Volume : 1  |  Issue : 1  |  Page : 7-10

Detection of extended spectrum β-lactamase production among uropathogens


Department of Microbiology, Pt. B.D.Sharma Post Graduate Institute of Medical Sciences, Rohtak-124 001, Haryana, India

Correspondence Address:
Ritu Aggarwal
Department of Microbiology, Pt. B.D.Sharma Post Graduate Institute of Medical Sciences, Rohtak-124 001, Haryana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2727.44423

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Background: Detection of extended spectrum β -lactamase (ESBL) production among uropathogens is an important marker of endemicity. Aim: Intervention of this endemic transmission is important for the control of initial outbreak of ESBL producing organisms in a hospital or specialized unit of hospital. Materials and Methods: During the study period of one and a half months, 1,551 urine samples were processed for significant bacteriuria. Two hundred gram negative bacterial isolates were tested for ESBL production. Antimicrobial sensitivity pattern was ascertained for ESBL producing isolates. Results: ESBL production was seen in 36% of isolates. All the isolates were multidrug resistant with uniform sensitivity to imipenem. Conclusion: This study reveals the significant prevalence of ESBL producing organisms in this north Indian tertiary care hospital. Constant revision of antibiotic policies with infection control interventions is suggested.


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