| ORIGINAL ARTICLE |
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| Year : 2010 | Volume
: 2
| Issue : 1 | Page : 25-30 |
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Lipid profile of type 2 diabetic and hypertensive patients in the Jamaican population
Lorenzo Gordon1, Dalip Ragoobirsingh2, Errol Y St A Morrison2, Eric Choo-Kang3, Donovan McGrowder3, E Martorell4
1 Department of Medicine, The University of the West Indies, Kingston 7, Jamaica
2 Basic Medical Sciences (Biochemistry Section), The University of the West Indies, Kingston 7, Jamaica
3 Department of Pathology, The University of the West Indies, Kingston 7, Jamaica
4 Department of Epidemiology, Provincial Centre of Hygiene and Epidemiology of Santiago de Cuba, Cuba
Correspondence Address:
Dalip Ragoobirsingh
Basic Medical Sciences (Biochemistry Section), The University of the West Indies, Kingston 7
Jamaica
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0974-2727.66709
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Aims : Previous studies have shown that diabetes mellitus (DM) increases the risk of cardiovascular diseases in females to a greater extent than in males. In this cross-sectional study, we evaluated the lipid profiles of type 2 diabetic males and females.
Materials and Methods : The study included 107 type 2 diabetic patients (41 males and 66 females), and 122 hypertensive type 2 diabetic patients (39 males and 83 females), aged 15 years and older. Total cholesterol (TC), triglycerides (TG), low density lipoprotein-cholesterol (LDL-C), very low density lipoprotein-cholesterol (VLDL-C) and high density lipoprotein-cholesterol (HDL-C) concentrations were assayed for each group using standard biochemical methods.
Results : The mean TC, TG, VLDL-C, HDL-C and LDL-C concentrations, TG/HDL and LDL/HDL ratios were higher in type 2 diabetic and hypertensive type 2 diabetic patients compared with non-diabetic, and hypertensive non-diabetic control subjects, although these were not significant (P > 0.05). Hypertensive type 2 diabetic females had significantly higher serum TC (7.42 ± 1.63 mmol/L) than hypertensive non-diabetic males (5.76±1.57 mmol/L; P < 0.05). All the other lipid and lipoprotein parameters except HDL-C were non-significantly higher in females with type 2 DM and those with hypertension and type 2 DM, compared with type 2 diabetic and hypertensive type 2 diabetic males, respectively (P > 0.05).
Conclusion : This study demonstrated that dyslipidemia exists in our type 2 diabetic population with greater TC in hypertensive type 2 diabetic females compared with hypertensive type 2 diabetic males. This suggests that hypertensive type 2 diabetic females are exposed more profoundly to risk factors including atherogenic dyslipidemia compared with males. |
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