Year : 2019 | Volume
: 11 | Issue : 2 | Page : 103--106
M2G1G2 white blood cell flag by three-part automated hematology analyzer: A hint to dengue infection in appropriate clinical context
Maitrayee Roy1, Akshay Bali2
1 Department of Pathology, M.M. Institute of Medical Sciences and Research, Ambala, Haryana, India
2 Department of Hematology, Maitri Diagnostic Lab, Ambala, Haryana, India
BACKGROUND: Automated hematology analyzers often generate many flags which can provide important clues to the underlying hematological abnormality. Although pathologists are generally well versed in recognizing the importance of flags indicating potential leukemic blasts, their utility in hinting toward infectious etiology, especially during epidemics, is less well known. We analyzed any abnormal flags generated by a three-part automated hematology analyzer in serologically confirmed cases of dengue.
MATERIALS AND METHODS: The study included 28 patients diagnosed with serologically confirmed dengue infection. The venous samples were run on ABX Miros-60 three-part hematology analyzer. The complete blood count data and any abnormal flags were noted and correlated with peripheral blood film findings in all patients.
RESULTS: An abnormal white blood cell (WBC) flag was noted in all 28 patients, including two in whom all other hematological parameters were within normal limits. In 26 (93%) patients, M2G1G2 WBC flag was noted while the samples of the remaining two patients generated M2G1 and L1M2G1G2 WBC flags, respectively.
CONCLUSION: An abnormal WBC flag, when correlated in appropriate clinical context, especially during a dengue outbreak, can aid in targeting the cohort of patients who will require immediate referral for serological confirmation.
Dr. Akshay Bali
Maitri Diagnostic Lab, First Floor Above Bali Clinic, Baldev Nagar, Ambala - 134 003, Haryana
|How to cite this article:|
Roy M, Bali A. M2G1G2 white blood cell flag by three-part automated hematology analyzer: A hint to dengue infection in appropriate clinical context.J Lab Physicians 2019;11:103-106
|How to cite this URL:|
Roy M, Bali A. M2G1G2 white blood cell flag by three-part automated hematology analyzer: A hint to dengue infection in appropriate clinical context. J Lab Physicians [serial online] 2019 [cited 2019 Sep 21 ];11:103-106
Available from: http://www.jlponline.org/article.asp?issn=0974-2727;year=2019;volume=11;issue=2;spage=103;epage=106;aulast=Roy;type=0